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GVHD

Developing an Automated Image Analysis Algorithm for Accurate Scoring of Chronic Graft-Versus-Host Disease

Chronic graft-versus-host disease (cGVHD) is the largest contributor to non-relapse–related long-term morbidity and mortality in patients who undergo allogeneic hematopoietic cell transplantation (HCT), with...

Cytokeratin-20 Plasma Levels Predicting Occurrence and Grade of Acute Graft-Versus-Host Disease

In a study led by Nikolett Lupsa, researchers aimed to address the unmet need in accurate predictive factors for acute graft-versus-host disease (aGVHD). They...

Mesenchymal Stromal Cells for Acute or Chronic Steroid-Resistant Graft-Versus-Host Disease

Mesenchymal stromal cells (MSCs) are being explored for their ability to treat graft-versus-host disease (GVHD), a serious complication which can arise after allogenic hematopoietic...

Determining the Optimal Anti-Thymocyte Globulin Exposure in Haploidentical Peripheral Blood Stem Cell Transplantation

Anti-thymocyte globulin (ATG) is used in conditioning prior to allogeneic hematopoietic stem cell transplantation for acute graft-versus-host disease (aGVHD) prophylaxis—however, ATG was shown to...

Mesenchymal Stromal Cells in Second-Line Therapy of Steroid-Resistant Acute Graft-Versus-Host Disease

Mesenchymal stromal cells (MSC) are being explored as a potential second-line therapy for steroid-resistant (SR) acute graft-versus-host disease (aGVHD). In a recent phase III...
woman receiving an Eyesight exam

Observing Outcomes and Complications in Phacoemulsification for Ocular Graft-Versus-Host Disease

Chronic ocular graft-versus-host disease (oGVHD) after allogeneic hematopoietic stem cell transplantation (aHSCT) is a serious complication that can negatively affect a patient’s vision. Phacoemulsification,...
doctor speaks to male patient in hospital bed while loved one stands next to him and holds his hand

Characterizing Chronic Graft-Versus-Host Disease Flares During Immunosuppressive Therapy

According to an article published in Bone Marrow Transplantation, the prolonged immunosuppressive therapy (IST) used to treat chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic...
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