This week on DocWire, editors spoke with Carole Wegner, PhD, HCLD, Vice President of Research and Grants Administration for the V Foundation for Cancer Research, to discuss canine comparative oncology, which explores the similarities and differences between human and canine cancers. The V Foundation was recently awarded three Comparative Oncology Research Consortium (CORC) grants toward work in this field.
In other news, researchers from Roswell Park Cancer Center published a study examining whether financial toxicity impacts survival in patients with head and neck cancer. They found that for patients with significant financial stress, the risk of mortality from cancer was nearly double. “Doctors should consider how financial toxicity may be impacting their patients and do everything we can to improve our patients’ quality of life, and we want to encourage patients to take advantage of financial counseling and every other resource that can lessen their burden,” said lead author Anurag Singh, MD.
A study published in the Journal of Pineal Research offered insight on why night shift workers are at increased risk of certain cancers. They found that night shifts disrupt natural 24-hour rhythms in the activity of certain cancer-related genes, making night shift workers more vulnerable to damage to their DNA while simultaneously causing the body’s DNA repair mechanisms to be mistimed to deal with that damage, thus augmenting the risk of developing malignancies.
Factors like hemoglobin level, BMI, age, and sex, could increase the risk of developing chemotherapy-induced peripheral neuropathy (CIPN) after cancer treatment, according to findings published in JAMA Network Open. Grade 1 or higher CIPN was reported in 71% of participants following treatment for breast, colorectal, and ovarian cancers. Low hemoglobin levels and higher BMI were associated more severe CIPN.