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Myeloproliferative Neoplasms

Intracellular Reactive Oxygen Species Profiles in Patients With Myelodysplastic Syndrome

Researchers developed a method to measure standardized intracellular reactive oxygen species (siROS) levels in the CD34+ bone marrow cells of patients with myelodysplastic syndrome...

Azacitidine With Or Without Enasidenib In Patients With Acute Myeloid Leukemia

Findings from a randomized trial, published in The Lancet Oncology, showed that combining enasidenib with azacitidine was well tolerated and significantly improved overall response...

Decitabine and Azacitidine in the Treatment of Chronic Myelomonocytic Leukemia

Researchers performed a meta-analysis to evaluate two hypomethylating agents (HMAs), decitabine and azacitidine, in the treatment of patients with chronic myelomonocytic leukemia (CMML). Their...
blood sample vile with words "Acute lymphomoblastic leukemia" below it

Gemtuzumab Ozogamicin in Treating Acute Myeloid Leukemia Subgroups

In a systematic review and meta-analysis, researchers assessed the efficacy and safety of gemtuzumab ozogamicin (GO) in treating patients with subtypes of acute myeloid...

LCL161 in Treating Patients With Myelofibrosis: Phase II Trial Results

A trial examined weekly administration of LCL161 therapy in a large, high-risk, older study population with myelofibrosis (MF), and found that it appears to...

Outcomes of Patients With Hematological Malignancies Developing COVID-19

In a clinical trial, researchers examined the characteristics and mortality rate of patients with hematological malignancies (HM) who developed SARS-CoV-2 disease 2019 (COVID-19). The...

Survival of US Patients With Myelofibrosis After Ruxolitinib Approval

A phase III trial assessed the overall survival in patients with myelofibrosis (MF) since ruxolitinib was approved by the US Food and Drug Administration...
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