Correlation Between Bolus Feeding and Splanchnic and Cerebral Oxygen Utilization Efficiency in Premature Anemic Infants Following Transfusion

A study assessed whether a correlation exists between feeding and splanchnic and/or cerebral oxygen utilization efficiency during anemia and/or after packed red blood cell transfusion. Twenty-five hemodynamically stable, bolus-fed preterm infants received packed red blood cell transfusions. An adverse relationship was observed between splanchnic fractional tissue oxygen extraction and feedings in the period immediately following transfusion. The researchers concluded that a correlation may exist between enteral feeding and gut ischemia and possibly transfusion-associated necrotizing enterocolitis.


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