Momelotinib prolonged overall survival (OS) and leukemia-free survival (LFS) in patients with myelofibrosis compared with danazol, an exploratory analysis of the MOMENTUM trial showed. The phase III study evaluated momelotinib, a Janus kinase (JAK) inhibitor, versus danazol, a pituitary gonadotropin inhibitor that is approved to treat anemia in myelofibrosis. The study included 195 patients who had myelofibrosis, anemia, and splenomegaly. At week 24, all patients who had received momelotinib showed spleen, symptom, and anemia ...
Myelofibrosis
Learn more about the newest discoveries and latest clinical insights in myelofibrosis (MF). Cancer Nursing Today provides up-to-date perspectives and information on transplant trends in MF, novel therapeutic targets, and more. From promising new treatments to risk factors and prognostics, explore the latest developments in MF care.
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Researchers developed and piloted a novel phone-delivered positive psychology intervention called PATH.
Interprofessional team-based care is the standard for patients undergoing HSCT. But who belongs on the team?
Higher baseline quality of life independently predicted longer overall survival in patients with myelofibrosis.
Pacritinib was found to be more effective than best available treatment at reducing spleen volume in myelofibrosis patients.
Adding navitoclax to ruxolitinib treatment in patients with persistent or progressive myelofibrosis led to durable splee
Myelofibrosis patients treated with fludarabine and busulfan along with TBI saw reduction in graft failure.
A trial examined weekly administration of LCL161 therapy in a large, high-risk, older study population with myelofibrosis ...
An analysis published in Annals of Hematology sought to add real-world context to findings from the phase II MYF2001 trial, ...
In a study published in Blood, investigators sought to define a new therapeutic target for the treatment of myelofibrosis ...
The JAK1/2 inhibitor ruxolitinib is a potent immunomodulator and effectively treats myeloproliferative disease such as ...
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