The addition of abatacept to calcineurin inhibitor/methotrexate-based graft-versus-host disease (GVHD) prophylaxis showed durable outcomes at 3 and 5 years after hematopoietic cell transplant (HCT) in the ABA2 clinical trial. Lev Gorfinkel, MD, of the Boston Children’s Hospital, and colleagues, reported relatively stable overall survival (OS), relapse, non-relapse mortality (NRM), chronic GVHD (cGVHD), and relapse-free survival (RFS) rates in nearly 200 adult and pediatric patients in this follow-up data. ...
GVHD
Explore the most recent clinical developments in graft-versus-host disease (GVHD). Cancer Nursing Today provides up-to-date coverage of biomarkers for GVHD, chronic GVHD flares during immunosuppressive therapy, and more. From disease prevention in pediatric patients to drug evaluation for chronic GVHD, learn more about the evolution of GVHD care and research.
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Kirk R. Schultz, MD, FCAHS, explains that multiple strategies for GVHD prevention and preemption are under investigation.
Risk factors for GVHD and its severity differ by donor type following allogeneic SCT with post-transplant PTCy prophylaxis.
Patients with pulmonary comorbidities and a history of smoking are at increased risk for chronic GVHD.
Piyanuch Kongtim, MD, PhD, shares insights from work she presented at the 2024 ASH Annual Meeting.
Irwin Walker, MBBS, joined Cancer Nursing Today at ASH 2024 to share his insights on the pilot trial and the next steps.
Patient-reported outcomes increased the risk of health care utilization and HCT-related complications, like GVHD, post HCT.
Chronic GVHD is less frequent in children than in adults, but its frequency has come down much more significantly in adults.
Noah Merin, MD, PhD, explains how the GVHD prophylaxis method has changed outcomes and shares nursing implications at ASH.
The study, presented at ASH 2024, showed that none of the patients experienced grade 3-4 GVHD.
Metabolite profiles may be promising as predictive biomarkers for clinical outcomes in patients post-HSCT at risk of GVHD.
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Elaine S. DeMeyer, RN, MSN, AOCN®, BMTCN®Elaine S. DeMeyer, RN, MSN, AOCN®, BMTCN®, is the owner of beyond Oncology Education, LLC.
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