Myeloproliferative Neoplasms (MPN)

Read the most current news and learn about the latest clinical research on myeloproliferative neoplasms (MPNs). Cancer Nursing Today offers up-to-date information on health-related quality of life in patients with MPNs, COVID-19 outcomes in patients with MPNs, and more. From molecular screening and clinical trials to the psychosocial impact of myeloproliferative neoplasms, learn how MPN care is moving forward.

Oxidative Stress in Older Patients with BCR-ABL Negative MPN

Oxidative Stress in Older Patients with BCR-ABL Negative MPN

Patrick Daly

MPN | December 20, 2021

Essential thrombocytosis (ET), polycythemia vera (PV), and primary myelofibrosis (PM) are BCR-ABL–negative myeloproliferative neoplasms (MPN) with the potential to develop into acute leukemia. The risk of progression is increased by oxidative stress and some genetic mutations. As oxidative stress increases with age, and the median age of patients with ET, PV, and PM is expected to soon pass 65 years, a research team led by Mahmut B. Koyuncu examined oxidative stress parameters in older patients with MPN. Their article, published in Clinical Laboratory, reported that serum ischemia modified albumin (IMA) and thiol levels are significantly changed in older patients with BCR-ABL–negative ...

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Oxidative Stress in Older Patients with BCR-ABL Negative MPN

Oxidative Stress in Older Patients with BCR-ABL Negative MPN

Patrick Daly

MPN | December 20, 2021

Essential thrombocytosis (ET), polycythemia vera (PV), and primary myelofibrosis (PM) are BCR-ABL–negative ...

Incidence of Abnormal B-Lymphoblasts in MDS and MPN

Incidence of Abnormal B-Lymphoblasts in MDS and MPN

Patrick Daly

MPN | December 20, 2021

According to Alexander Chan, MD, and colleagues from the Department of Pathology at the Memorial Sloan Kettering Cancer ...

Gene Variant Frequency May Predict VT Risk in Polycythemia Vera Patients

Gene Variant Frequency May Predict VT Risk in Polycythemia Vera Patients

Patrick Daly

MPN | December 20, 2021

In patients with polycythemia vera (PV), arterial thrombosis (AT) and venous thrombosis (VT) events are common complications ...

Abnormal Signatures of Extracellular Vesicles in Polycythemia Vera

Abnormal Signatures of Extracellular Vesicles in Polycythemia Vera

Patrick Daly

MPN | December 20, 2021

Polycythemia vera (PV) is subject to the chronic inflammation commonly observed in other myeloproliferative neoplasms. Recent ...

Arsenic Trioxide and Chemotherapy Quality of Life Outcomes in Acute Promyelocytic Leukemia

Arsenic Trioxide and Chemotherapy Quality of Life Outcomes in Acute Promyelocytic Leukemia

Patrick Daly

MPN | December 7, 2021

In a follow-up to the randomized controlled trial APL0406, researchers compared long-term health-related quality of life of ...

Entinostat Plus Clofarabine for Acute Lymphoblastic or Biphenotypic Leukemia

Entinostat Plus Clofarabine for Acute Lymphoblastic or Biphenotypic Leukemia

Patrick Daly

MPN | December 7, 2021

A phase I study tested low dose clofarabine with escalating doses of entinostat in adults with Philadelphia ...

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