Researchers are working to establish a WGS sarcoma database to facilitate improved access to clinical trials. Researchers found that patients within a certain age group were least likely to receive a timely imaging study. Cancers of unknown primary pose a “significant challenge due to poor clinical outcomes and limited treatment options." Psychosocial care and support are critical parts of cancer care, according to the International Psycho-Oncology Society. Certain patients are less likely to use hospice services, but oncology nurses can help ensure the option is made available. Study participants identified several barriers when it came to implementing a suicide risk screening. Does the route of administration for HER2 targeted therapy affect overall and progression-free survival? Certain intrinsic molecular subtypes changed after metastasis compared to the primary tumor subtype. Overall survival was the least favorable when brain metastasis was diagnosed during or after second-line treatment. Social determinants of health affect outcome disparities more than race and ethnicity. But what are they? Quitting smoking after diagnosis leads to better survival, lower toxicity, and fewer adverse effects of treatment. HPV is a major cause of head and neck cancer. What should you be aware of when discussing HPV prevention with your patients? As tobacco and alcohol use trend downward, a higher proportion of oropharyngeal cancer due to HPV infection is being noted. Most men with prostate cancer report that active surveillance improves anxiety and quality of life, but not all. A new cancer drug can halt disease progression and has a low rate of toxicity, giving hope to those with RET gene mutations. The combination of chemo- and radiotherapy can cause oral mucositis. Luckily a remedy may be in the fridge. The smoothened protein-which acts as a cell communication system-blocks a signaling enzyme called the PKA catalytic subunit. Topical use of aloe vera gel significantly reduced radiation-induced skin toxicities in head and neck cancer patients. Brain tumors are the most common solid tumors affecting children. at this point it remains unclear if intubation and more aggressive care could improve survival.